Use Modafinil (Provigil) accurately as directed within the label, or as prescribed by your physician. Tend not to use in greater or smaller sized quantities or for for a longer period than advised.
Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.
Akutt og alvorlig allergisk reaksjon med symptomer som feber, utslett, opphovning, pustebesvær og blodtrykksfall. Anafylaktisk sjokk er livstruende om male ikke setter i gang med legemiddelbehandling i sort av antihistaminer og adrenalin.
It has antioxidant Attributes that could decrease the existence of harmful free of charge radicals from the Mind tissue, rendering it a powerful neuroprotectant.[25]
Prevent concomitant use of tucatinib with CYP3A substrates, in which minimal concentration variations may perhaps cause severe or daily life-threatening toxicities. If unavoidable, reduce CYP3A substrate dose In line with product labeling.
Orexin/Hypocretin: A lot of modafinil’s wakefulness-advertising and marketing motion is attributable to its motion over the Mind’s orexin/hypocretin program, which is found in the hypothalamus which is to blame for regulating wakefulness, arousal, and hunger.
This medicine may perhaps impair your pondering or reactions. Watch out for those who generate or do everything that needs you to be alert.
modafinil will improve the stage or effect of diazepam buccal by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Watch. Strong or reasonable CYP2C19 inhibitors may perhaps reduce charge of diazepam elimination, therefore expanding adverse reactions to diazepam.
nelfinavir will raise the amount or result of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. more info Use Caution/Check.
etravirine will reduce the level or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
cannabidiol will improve the level or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Intently. Consider cutting down the dose of sensitive CYP2C19 substrates, as clinically acceptable, when coadministered with cannabidiol.
Stiripentol is often a CYP3A4 inhibitor and inducer. Check CYP3A4 substrates coadministered with stiripentol for greater or reduced outcomes. CYP3A4 substrates may perhaps demand dosage adjustment.
Influence of coadministration of a twin CYP3A4 and CYP2C19 inhibitor with fedratinib hasn't been studied.
modafinil will enhance the amount or impact of diazepam intranasal by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Powerful or moderate CYP2C19 inhibitors may possibly lessen charge of diazepam elimination, thus rising adverse reactions to diazepam.